The Chemical Genomics Centre (CGC) consists of four independent research groups hosted by the Max Planck Institute of Molecular Physiology in Dortmund, Germany. The CGC was established in 2005 by the Max Planck Society (MPG) in collaboration with several pharmaceutical and agrochemical companies to promote collaborations between Academia and Industry as key to innovative scientific research.

The mission of the CGC is to address challenging scientific problems in the field of chemical biology and to explore and validate high-risk approaches to cutting-edge precompetitive research, which could enable the generation of translational science in the medium to long term. This includes the development of innovative chemical methods, novel biology and assay methods, and the discovery of novel targets.

The CGC empowers talented research groups to develop their ambitious and innovative scientific projects in a unique set up. The CGC interconnects the new research groups with the scientific, infrastructural and institutional strength of the Max Planck Institute of Molecular Physiology in Dortmund (MPI) and directly benefits from the developing Dortmund Science Hub and from the scientific expertise of the industrial partners.

The CGC was set up as a 5 years project. After two successful funding periods (CGCI: 2005-2010; CGCII: 2012-2017) a third funding period of the CGC (CGCIII) was established in October 2018 as a partnership between the MPG and MPI, and the companies AstraZeneca, Merck KGaA and Pfizer. The CGCIII supports 4 newly-established independent research groups led by Malte Gersch, Jochen Imig, Peter ‘t Hart and Peng Wu.


Dr. Peter 't Hart
Identification and Optimization of Inhibitors
of Protein-RNA Interactions.
Dr. Malte Gersch
Therapeutic Targeting of Proteolysis in the Ubiquitin System.
Dr. Peng Wu
Targeting Protein-RNA Interactions Using Small Molecule-Based Strategies.
Dr. Jochen Imig
Systems Biology of LncRNA and MiRNA Networks in

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