Dr. Peng Wu will receive research funding from the Exploration Grants programme of the Boehringer Ingelheim Foundation
Dr. Peng Wu will receive research funding from the Exploration Grants programme of the Boehringer Ingelheim Foundation to support the project “Small molecules modulate the RNA-binding protein-mediated degradation of mRNA”.
RNA modifications affect a myriad of cellular activities related to RNA metabolism. This Exploration Grant project aims to target the RNA-binding proteins that recognize the mRNA modifications for the identification of small-molecule inhibitors and activators. Such small molecules will be evaluated as potential hits for tools to probe the regulatory network involving these RNA-binding proteins that mediate mRNA-degradation and as hits for therapeutics for the treatment of human diseases such as in neurological disorders and viral infections that are associated with dysregulation of such RNA-binding proteins.
About the Foundation
The Boehringer Ingelheim Foundation is a legally independent, non-profit foundation committed to the promotion of the medical, biological, chemical, and pharmaceutical sciences. It was established in 1977 by Hubertus Liebrecht, a member of the shareholder family of the Boehringer Ingelheim company. With the Perspectives Programme Plus 3 and its Exploration Grants, the foundation supports independent junior group leaders