Wu Lab

Wu Lab

PUBLICATIONS

Selected publications from 2019 to 2020 (*corresponding author; #equally contributed authors):

40
P. Wu
*. Inhibition of RNA-Binding Proteins with Small Molecules. Nat. Rev. Chem. 2020, in press. DOI:10.1038/s41570-020-0201-4.

39
S. Siriwardena#, D. Godage#, V. Shoba#, S. Lai#, M. Shi, P. Wu, S. Chaudhary, S. L. Schreiber, A. Choudhary*. Inhibition of RNA-Binding Proteins with Small Molecules. J. Am. Chem. Soc. 2020, in press. DOI:10.1021/jacs.0c05537.

38
P. Wu*, M. Givskov, T. E. Nielsen*.  Reactivity and Synthetic Applications of Multicomponent Petasis Reactions. Chem. Rev. 2019, 119, 11245-11290. DOI: 10.1021/acs.chemrev.9b00214.

37
P. Wu#, W. E. Bjorn-Yoshimoto#, M. Staudt, A. A. Jensen*, L. Bunch*. Identification and structure-activity relationship study of imidazo[1,2-α]pyridine-3-amines – as first selective inhibitors of excitatory amino acid transporter subtype 3 (EAAT3). ACS Chem NeuroSci. 2019, 10,4414-4429. DOI: 10.1021/acschemneuro.9b00447.

36
B. Maji, S. Gangopadhyay#, M. Lee#, M. Shi#, P. Wu#, R. heler, B. Mok, D. Lim, S. Siriwardena, B. Paul, V. Dančík, A. Vetere, M. Mesleh, L. A. Marraffini, D. R. Liu, R. A. Clemons, B. K. Wagner, A. Choudhary*. A high-throughput platform to identify inhibitors of CRISPR-Cas9. Cell 2019, 177, 1067-1079.E19. DOI: 10.1016/j.cell.2019.04.009

Before 2020 and Full List of Publications  >>>

BOOK CHAPTERS:

3.    P. Wu*, P. Diner, L. Bunch, Chapter 3. The Screening and Design of Allosteric Kinase Inhibitors
       Kinase Drug Discovery: Modern Approaches
       Edited by R. A. Ward and F. Goldberg
       Royal Society of Chemistry, London, 2019, Pp. 34-60
       DOI: 10.1039/9781788013093-00034

 

2.    P. Wu*, A. Choudhary*, Chapter II.2.
       Successful Drug Discovery, Volume 3
       Edited by J. Fischer, C. Klein and W. E. Childers
       Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2018, Pp. 65-93
       DOI: 10.1002/9783527808694.ch3

 

1.    P. Wu*, M. Givskov, T. E. Nielsen*, Chapter 2.4.2
       Drug Selectivity – An Evolving Concept in Drug Discovery
       Edited by N. Handler and H. Buschmann
       Book in Series Methods and Principles in Medicinal Chemistry, ISSN: 1865-0562    
       Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 2017, Pp. 33-53
       DOI: 10.1002/9783527674381.ch2

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